01 - Combine smoked paprika, garlic powder, onion powder, chili powder, cumin, black pepper, kosher salt, and brown sugar in a small bowl.
02 - Pat the brisket dry with paper towels, then evenly rub the spice mixture over the entire surface of the meat.
03 - In a separate bowl, whisk together ketchup, apple cider vinegar, brown sugar, Worcestershire sauce, Dijon mustard, molasses, liquid smoke, beef broth, garlic powder, onion powder, black pepper, and salt until smooth.
04 - Place the brisket in the slow cooker with the fat side facing up. Pour the BBQ sauce over the brisket, ensuring full coverage.
05 - Cover and cook on low setting for 8 hours, or until the brisket is tender to the touch.
06 - Remove the brisket from the slow cooker and allow it to rest for 10 minutes to retain juices.
07 - Cut the brisket against the grain into slices or shred as preferred.
08 - Skim any excess fat from the sauce in the slow cooker and spoon it over the brisket before serving.